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MRCP (UK), FRCP (Glasgow), CCT (Hepatology, UK)
Hepatology, Liver Disease & Transplantation
Director – Hepatology
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Brief Profile
Dr. Dinesh Jothimani is a UK- and Australia-trained hepatologist with over 18 years of clinical experience in managing complex liver diseases and performing liver transplants. He is highly skilled in therapeutic endoscopies, including over 500 ERCPs, and has deep clinical expertise in Acute Liver Failure, Viral Hepatitis, Autoimmune Hepatitis, and advanced transplant hepatology.
A graduate of Madras Medical College under the Tamil Nadu Dr. M.G.R. Medical University (2000), Dr. Dinesh earned his MRCP (UK) in 2004, followed by his CCT in Hepatology, Gastroenterology, and General Medicine from the West Midlands Deanery in the UK. He was conferred the prestigious FRCP (Glasgow) in 2018. His outstanding contributions to liver care earned him the Times Health Excellence Award for Service Excellence in Liver & Gastro Care in 2020.
Dr. Dinesh is actively engaged in the global hepatology community. He is a member of the Royal College of Physicians (London), Royal College of Physicians and Surgeons (Glasgow), General Medical Council (UK), and various leading societies such as the European Association for the Study of the Liver (EASL), American Association for the Study of Liver Diseases (AASLD), Liver Transplant Society of India (LTSI), and Indian Association for the Study of Liver (INASL). He also served as Honorary Secretary of the Indian Medical Association – Global Hospital Branch.
Educational Qualifications
- FRCP (Glasgow) – June 2018
The Royal College of Physicians and Surgeons, Glasgow - CCT (Hepatology, Gastroenterology & General Medicine) – 2004 to 2010
West Midlands Deanery, United Kingdom - MRCP (UK) – April 2004
The Royal College of Physicians, United Kingdom - MBBS – 1994 to 2000
Madras Medical College & Government General Hospital, Dr. MGR Medical University, Chennai, India
Clinical Expertise
Procedures Performed Competent Practitioner
- ERCP (total 500)
- OGD (diagnostic and therapeutic) (total >1000)
- Colonoscopy (total 600)
- Transient elastography (Fibroscan)
- Percutaneous Liver Biopsy (>350)
- Abdominal paracentesis
- Central lines (internal jugular, subclavian, femoral and long lines)
- Arterial line
- Swan-Ganz catheter
- Temporary pacing wire insertion
- DC cardioversion (emergency)
Laboratory Skills
- Immunohistochemistry
- Immunofluorescence
- RT-PCR and bench PCR
- Reverse Transcription
- Gel Electrophoresis and restriction enzyme digestion
Accomplishments
Affiliations and Memberships
Present position
Honors and Awards
Editorial Work and Reviewer
Innovation
Associated Publications
Research and Publication
Publications
- Liver in Systemic disease: Managing the patient with unexplained abnormal serum liver tests in secondary care – Elsevier Textbook Chapter, February 2022
- Hepatitis NonA–E viruses – Textbook Chapter, INEDSYS Hepatology: A Comprehensive Textbook, January 2022
- Post-Liver transplant Viral infections – Textbook Chapter (submitted, August 2021)
- NASH: A rapidly increasing indication for Liver transplantation in India – JCEH, September 2021
- Autoimmune hepatitis following COVID vaccination – Journal of Autoimmunity, July 2021
- Reply letter: Optimal diagnostic tool for oesophageal varices during COVID-19 – Clinical Radiology, June 2021
- COVID-19: Elevated Von Willebrand factor at hospital admission predicts clinical outcome – JAPI, May 2021
- Optimal diagnostic tool for oesophageal varices during COVID-19 – Clinical Radiology, March 2021
- Versatility of Anabolic steroids induced Hepatotoxicity – JCEH, March 2021
- Severe jaundice in a COVID-19 patient – JCEH, February 2021
- Therapeutic plasma exchange in EAD – Experimental and Clinical Transplantation, February 2021
- LTSI guidelines in the management of ALI in Yellow phosphorus poisoning – JCEH, December 2020
- First report of toxin induced graft injury following LT – Hepatology, September 2020
- Post Liver transplant recurrent and de novo viral infections – Best Practice Gastro & Hepatology, September 2020
- COVID-19: Poor outcomes in patients with Zinc deficiency – IJID, August 2020
- COVID-19 and decompensated cirrhosis – Hepatology International, August 2020
- Lockdown effects on Liver transplant recipients – JAPI, July 2020
- COVID-19 and Liver – Journal of Hepatology, June 2020
- Acute Liver Failure – INASL Consensus – JCEH, 2020
- Genetics of NASH – Textbook Chapter, 2019
- Post Liver Transplant Refractory Anemia – Case report, JCEH, 2019
- Haemospray in difficult variceal bleed – Case report, 2018
- Management of post liver transplant recurrent HCV infection with directly acting antiviral drugs – Hepatology International, 2016
- Delayed serological transfusion reaction due to anti-e – Indian Journal of Haematology and Blood Transfusion
- Textbook Chapter on Liver Regeneration – Elsevier Liver Transplantation, September 2015
- Role of Mycophenolate mofetil in Autoimmune hepatitis – An observational study – JCEH, June 2014
- A new era in the management of chronic hepatitis C – A review – Indian Journal of Gastroenterology, March 2013
- Macrophage secretory products induce an inflammatory phenotype in hepatocytes – World Journal of Gastroenterology, April 2012
- Non-invasive assessment of fibrosis in liver grafts due to hepatitis C recurrence – Clinical Transplantation, May 2011
- Treatment of Autoimmune hepatitis – A review of current and evolving therapies – Journal of Gastroenterology & Hepatology, 2010
- Reply letter: Early use of TIPS in cirrhotic patients with variceal bleeding – New England Journal of Medicine, 2010
- Reply letter: Outcome of recurrent hepatitis C virus after liver transplantation – Liver Transplantation, 2010
- Magnetic resonance imaging and spectroscopy in steatosis and fibrosis – Journal of Hepatology, 2009
- An unusual case of gastric erosions – Gut, 2009
- Effect of ethnicity on oesophageal and gastric cancer management – European Journal of Gastroenterology & Hepatology, 2009
- Long-term immunosuppression for prevention of non-viral disease recurrence – Transplantation Proceedings, 2005
- A case report of hypertension associated with hypokalemia and hyponatremia – CME Geriatric
Medicine, 2005
Trials, Studies and Audits
- NASH and Liver transplantation (ongoing, 2020)
- Effect of Cardiovascular disease in NASH transplant patients (ongoing, 2020)
- COVID-19 and Liver (2020)
- Effect of Lockdown in liver transplant recipients (2020)
- Efficacy of Terlipressin in variceal bleed (2019)
- Leukocyte esterase strip test for rapid diagnosis of SBP (2017–2018)
- Hepatitis E in post liver transplant patients
- NASH in healthy liver donors (2016)
- Outcome of Acute Liver Failure due to Rat Killer Poisoning – Global Hospitals, Chennai
- BMI and Liver Transplantation Outcome – Global Hospitals, Chennai
- Markers of significant steatosis in potential liver donors – Global Hospitals, Chennai
- Outcome of combined liver kidney transplantation – Global Hospitals, Chennai
- TMC-435 study – Protease inhibitor triple therapy in chronic hepatitis C – Principal Co-investigator, Derriford Hospital, Plymouth, UK
- Role of Budesonide in Autoimmune hepatitis – Southwest Liver Unit, Derriford Hospital, 2010
- ERCP practice audit, Southwest England – Derriford Hospital, 2010
- Efficacy of MMF in refractory Autoimmune hepatitis – Derriford Hospital, 2010
- Effect of weight loss prior to antiviral treatment in obesity and chronic hepatitis C – Brisbane, Australia, 2009
- Kupffer cells in obesity-related liver injury – Brisbane
- Response factors to antiviral treatment in chronic hepatitis C
- MRI for liver fibrosis assessment
- Portal Tract Lymphoid Tissue (PALT) in chronic hepatitis C cirrhosis – University of Birmingham
Posters
- Changing trend of liver transplantation in India – ILTS 2020, Turkey
- Cardiometabolic risk profile in transplant patients – ILTS 2020, Turkey
- Therapeutic plasma exchange in DILI – INASL 2018
- Non-invasive markers of liver fibrosis – INASL 2018
- Outcome of AIH-transplanted patients – INASL 2018
- Post transplant Parvovirus infection – INASL 2018
- Predictive factors of NAFLD in healthy donors – EASL 2016, Barcelona
- NASH in potential donors – ILTS 2016, Seoul
- BMI effect on post-transplant outcomes – ILTS 2014, London
- Predictive factors for significant steatosis – ILTS 2014 & EASL 2014, London
- Combined liver kidney transplantation – ILTS 2013, Sydney
- Variations in autoimmune hepatitis presentation – INASL 2013
- Transient Elastography in Indian patients – INASL 2012
- Budesonide in Autoimmune Hepatitis – APASL 2011, Bangkok
- MMF in Autoimmune Hepatitis – APASL 2011, Bangkok & BASL 2010, Edinburgh
- ERCP practice audit – AUGIS 2010
- Sensitivity of EUS in esophageal cancer – Midlands 2008
- Raised ALT in type 2 diabetes mellitus – Midlands 2008
- Case reports – Midlands 2007–2008
- Control of CDAD in UK hospital – UEGW Paris 2007
- Effect of TPN monitoring – UEGW Paris 2007
Oral Presentations
- NASH for diabetologists – Chennai Diabetic Association, 2019
- Post Liver Transplant Management – Gut Club Kolkata & Trivandrum, 2019
- Cirrhotic Cardiomyopathy – INASL 2018
- Hepatitis E in transplant patients – WCOG Abu Dhabi, 2016
- Acute Liver Failure due to Yellow Phosphorus – ILTS 2014, London
- Debate: N-acetyl cysteine in non-paracetamol ALF – INASL 2014, Jaipur
- Management of ALF – INASL 2013, Hyderabad
- Outcome of CLKT – ISOT 2012, Mumbai
- Molecular pathogenesis in HCC – INASL 2012, Guwahati
- Drug induced liver injury – UHCW, 2010
- ERCP practice audit – Southwest meeting, 2010
- MMF in AIH – Southwest meeting, 2010
- Weight loss & antiviral response – BILG Brisbane, 2009
- Control of CDAD – Midlands meeting, 2007
- Benign biliary strictures – Gut Club, 2006
- Paracetamol overdose outcome – QE UHB, Birmingham, 2005
Courses and Conferences Attended
- Master Class in Liver Disease, Chennai (annual, from 2012)
- EASL 2016, Barcelona | ILTS 2014 & 2017, London | EASL 2014, London
- ISOT 2012 | INASL (annual, from 2012)
- Best of DDW 2011, Hyderabad | APASL 2011, Bangkok
- ERCP course (hands on, 2010)
- BASL 2010, Edinburgh & School of Hepatology, Cambridge
- King’s Liver Course 2010, London | BASL 2009, London
- Queensland Hepatology 2009 | Melbourne Liver Fibrosis 2009
- Brisbane Liver Group 2008 & 2009 | Case by Case, Sydney 2009
- Australian Gastroenterology Week 2008, Brisbane
- Leadership & Management Course, Warwick, 2008
- BSG 2005, 2006, 2008 | UEGW 2007, Paris
- Midlands meetings 2005–2008
- National Gastroenterology Conference 2007, Edinburgh
- Upper GI Endoscopy 2005, Wolverhampton
- Medical Emergencies 2002, UCL London
Experience
- Dr. Rela Institute & Medical Centre (RIMC), Chennai
Director – Hepatology
12th September 2018 – Present - Institute of Liver Disease and Transplantation, Global Hospitals, Chennai
Consultant – Liver Transplant Physician
4th August 2012 – September 2018 - University Hospitals of Coventry & Warwickshire, UK
Consultant – Hepatologist (Locum)
October 2010 – February 2011 - West Midlands Deanery, Russell’s Hall Hospital, Dudley
Specialist Registrar – Gastroenterology & General Internal Medicine
September 2010 – September 2010 - South West Liver Unit, Derriford Hospital, Plymouth
Specialist Registrar – Hepatology (RCP Accredited NTN)
September 2009 – August 2010 - Princess Alexandra Hospital, Brisbane, Australia
Hepatology Research Fellow
August 2008 – August 2009 - Institute of Biomedical Research, University of Birmingham
Honorary Hepatology Research Fellow – Liver Labs
August 2007 – August 2008 - West Midlands Deanery, City Hospital, Birmingham
Specialist Registrar – Gastroenterology & General Medicine
June 2007 – August 2008 - West Midlands Deanery, Manor Hospital, Walsall
Specialist Registrar – Gastroenterology & General Medicine
June 2006 – June 2007 - West Midlands Deanery, Mid-Staffordshire General Hospital, Stafford
Specialist Registrar – Gastroenterology & General Medicine
June 2005 – June 2006 - Liver Unit, Queen Elizabeth Hospital, Birmingham
Specialist Registrar – Hepatology
August 2004 – June 2005 - Sherwood Forest NHS Trust, Kings Mill Hospital
Senior House Officer – Medical Rotation
August 2002 – August 2004 - Birmingham Heartlands & Solihull NHS Trust
Senior House Officer – General Medicine
February 2002 – August 2002 - Medway Maritime Hospital, Gillingham, Kent
House Officer – General Medicine
August 2001 – February 2002 - Leicester General Hospital, University Hospitals of Leicester, Leicester
Senior House Officer – Nephrology
June 2001 – July 2001 - Kettering General Hospital, Northants
Clinical Observership – Accident & Emergency
February 2001 – April 2001 - Madras Medical College & Govt. General Hospital, Chennai
Senior House Officer – General Medicine
May 2000 – October 2000 - Madras Medical College & Govt. General Hospital, Chennai
Pre-Registration House Officer
January 1999 – January 2000
