Dr. Santhosh Sampath

Educational Qualifications

• FANMB (Asian Nuclear Medicine Board)
  2017
  
• FEBNM (European Board of Nuclear Medicine)
  2016
  
• MD (Nuclear Medicine)
  Post Graduate Institute of Medical Education and Research, Chandigarh
  2011
  
• MBBS
  Stanley Medical College, Chennai, Tamil Nadu
  2008

Clinical Expertise

Advanced Nuclear Medicine Imaging

• PET/CT (Positron Emission Tomography – Computed Tomography)
  
• SPECT/CT (Single Photon Emission Computed Tomography – CT)
  
• Hybrid Imaging for Early Disease Detection
  

Radionuclide Therapy

• Radioiodine Therapy for Thyroid Disorders (Hyperthyroidism, Thyroid Cancer)
  
• Peptide Receptor Radionuclide Therapy (PRRT) for Neuroendocrine Tumors
  
• Samarium, Strontium, and Radium Therapy for Bone Metastases
  

Molecular Imaging in Oncology & Cardiology

• Oncological Imaging (Staging, Restaging, Response Assessment in Cancer)
  
• Cardiac PET Imaging (Myocardial Perfusion, Viability, Sarcoidosis)
  
• Molecular Imaging for Infection & Inflammation
  

Thyroid & Neuroendocrine Tumor Imaging and Therapy

• Thyroid Scintigraphy & Whole-Body Radioiodine Scans
  
• Neuroendocrine Tumor Imaging with Ga-68 DOTATATE PET/CT
  
• Radionuclide Therapy for Functional and Metastatic Tumors
  

Targeted Radionuclide Therapies

• Lu-177 DOTATATE Therapy for Neuroendocrine Tumors
  
• Lu-177 PSMA Therapy for Prostate Cancer
  
• Novel Targeted Radiopharmaceuticals for Precision Oncology (Alpha therapy: Actinium; Terbium)

Accomplishments

Affiliations and Memberships

Present position

Honors and Awards

Editorial Work and Reviewer

Innovation

Associated Publications

Research and Publication

Research Interests

A) Role of FDG-PET/CT

• Characterization of pancreatic lesions in areas of high incidence of pancreatic tuberculosis
  
• Detection and prognostication of recurrent pancreatic carcinoma
  
• Management of Takayasu arteritis
  

B) General Nuclear Medicine

• HIDA scan in the evaluation of Sphincter of Oddi Dysfunction
  
• MUGA-SPECT in the diagnosis and follow-up of dilated cardiomyopathy, especially RVEF, and evaluation of dyssynchrony
  
• Easy diagnosis of CRPS with three-phase bone scan
  
• Factors of MPI affecting ejection fraction recovery following revascularization
  

Thesis

Role of FDG-PET/CT in the characterization of pancreatic mass-forming lesions
2009–2011

Presentations

International – Oral Presentations

• Usefulness of PET/CT in preoperative staging of NSCLC patients – Society of Nuclear Medicine, Salt Lake City, USA (June 2010)
  
• Clinical validation of gated blood pool SPECT QBS software: correlation with MUGA and first-pass RNV – European Association of Nuclear Medicine, Vienna, Austria (October 2010)
  
• FDG-PET/CT based management of Takayasu Arteritis – Society of Nuclear Medicine, Miami, USA (June 2012)
  
• Role of FDG-PET/CT in the characterization of pancreatic mass-forming lesions: An experience from the tropics – Radiological Society of North America, Chicago, USA (November 2012)
  
• Utility of 18F-FDG-PET/CT in the detection and prognostication of recurrence of pancreatic cancer – Radiological Society of North America, Chicago, USA (November 2012)
  
• FDG PET/CT in the initial staging of pancreatic carcinoma – European Association of Nuclear Medicine, Barcelona, Spain (October 2016)
  
• Utility of NH3-FDG mismatch PET in prediction of improvement in LVEF post CABG – Asia-Oceania Congress of Nuclear Medicine and Biology, Yokohama, Japan (October 2017)
  
• FDG PET/CT vs CECT in the initial staging of pancreatic adenocarcinoma – Asia-Oceania Congress of Nuclear Medicine and Biology, Yokohama, Japan (October 2017)
  

National – Oral Presentations

• Usefulness of PET/CT in preoperative staging of NSCLC patients – Association of Nuclear Medicine Physicians of India, Bangalore (September 2009)
  
• Clinical validation of gated blood pool SPECT QBS software: correlation with MUGA and first-pass RNV – Society of Nuclear Medicine India, Chandigarh (November 2010)
  
• Cholescintigraphy in biliary dyskinesia: a reappraisal – Society of Nuclear Medicine India, 2010
  
• 18F-FDG-PET/CT in the diagnosis and follow-up of Takayasu arteritis – Society of Nuclear Medicine India, Chennai (December 2011)
  

Publications

• Manohar K, Mittal BR, Santhosh S, Bhattacharya A, Malhotra P, Varma S. 18F-FDG PET/CT in a rare case of diffuse large B cell lymphoma presenting as deep vein thrombosis with bilateral breast involvement and subcutaneous nodules. Hell J Nucl Med. Sep-Dec 2010;13(3):298-299.

• Mittal BR, Santhosh S, Kashyap R, Bhattacharya A, Singh B, Bahl A. Ventricular ejection fraction in patients with dilated cardiomyopathy calculated by gated blood pool SPET processing software: correlation with multigated acquisition and first pass radionuclide ventriculography. Hell J Nucl Med. Sep-Dec 2011;14(3):234-238.

• Santhosh S, Bhattacharya A, Bhadada S, Kaur R, Singh M, Mittal BR. Threephase skeletal scintigraphy in pachydermoperiostosis. Clin Nucl Med. Dec 2011;36(12):e199-201.

• Santhosh S, Guha P, Bhattacharya A, Bawa M, Mittal BR. False-positive “halo” sign on testicular scintigraphy in a 5-year-old boy with epididymitis and hydrocele. Indian J Nucl Med. Jul 2011;26(3):159-160.

• Santhosh S, Mittal BR, Bhattacharya A, Das A, Kochhar R. Importance of diffuse versus focal F-18 fluoro-deoxy-glucose uptake in oesophagus. Indian J Nucl Med. Oct 2011;26(4):211.

• Santhosh S, Mittal BR, Kamaleshwaran KK, Parghane R, Bhattacharya A, Singh B. Scintigraphic demonstration of ectopic thyroid tissue in a thyroglossal duct cyst in the presence of a normal thyroid. Clin Nucl Med. Dec 2011;36(12):1142-1143.

• Santhosh S, Mittal BR, Kashyap R, Bhattacharya A, Singh B. Symmetric increased skeletal muscular uptake of F-18 fluoro-deoxyglucose: A clue for the diagnosis of Graves’ disease. Indian J Nucl Med. Jul 2011;26(3):155-156.

• Santhosh S, Mittal BR, Shankar P, et al. (18)F-FDG PET/CT in bilateral primary adrenal T-cell lymphoma. Hell J Nucl Med. May-Aug 2011;14(2):166-167.

• Rana SS, Bhasin DK, Rao C, Sampath S, et al. Splenic tuberculosis diagnosed by endoscopic ultrasound-guided fine needle aspiration. Endoscopic ultrasound. Oct 2012;1(3):167-168.

• Rana SS, Bhasin DK, Rao C, Sampath S, et al. Autoimmune pancreatitis presenting with gastric outlet obstruction. Gastrointest Endosc. May 2012;75(5):1122-1123.

• Rana SS, Bhasin DK, Srinivasan R, Sampath S, Mittal BR, Singh K. Distinctive endoscopic ultrasound features of isolated pancreatic tuberculosis and requirements for biliary stenting. Clin Gastroenterol Hepatol. Mar 2012;10(3):323- 325.

• Rao CAS, Rana SS, Bhasin DK, Sampath S, et al. Mediastinal lymphadenopathy in ampullary adenocarcinoma: not always metastatic. Ann Gastroenterol. 2012;25(2):167-169.

• Santhosh S, Bhattacharya A, Gupta V, Singh R, Radotra BD, Mittal BR. Incidental detection of a bleeding gastrointestinal stromal tumor on Tc-99m red blood cell scintigraphy. Indian J Nucl Med. Oct 2012;27(4):269-271.

• Santhosh S, Mittal BR, Arun S, Sood A, Bhattacharya A, Kochhar R. Quantitative cholescintigraphy with fatty meal in the diagnosis of sphincter of Oddi dysfunction and acalculous cholecystopathy. Indian J Gastroenterol. Jul 2012;31(4):186-190.

• Arun S, Santhosh S, Sood A, Bhattacharya A, Mittal BR. Added value of SPECT/CT over planar Tc-99m mebrofenin hepatobiliary scintigraphy in the evaluation of bile leaks. Nucl Med Commun. May 2013;34(5):459-466.

• Bhoil A, Mittal BR, Bhattacharya A, Santhosh S, Patel F. Role of F-18 fluorodeoxyglucose positron emission tomography/computed tomography in the detection of recurrence in patients with cervical cancer. Indian J Nucl Med. Oct 2013;28(4):216-220.

• Mohan JR, Santhosh S, Sood A, Bhattacharya A, Mittall BR. Pertechnetate thyroid scan in Marine-Lenhart syndrome. Indian J Nucl Med. Apr 2013;28(2):125- 126.

• Rana SS, Chaudhary V, Gupta N, Sampath S, Mittal BR, Bhasin DK. Pancreatic tuberculosis presenting as an unusual head mass. Endoscopy. 2013;45 Suppl 2 UCTN:E317-318.

• Sampath S, Harisankar CN, Bhattacharya A, Gupta R, Mittal BR. F-18 fluorodeoxyglucose positron emission tomography/computed tomography in the staging of linitis plastica caused by primary gastric adenocarcinoma. World J Nucl Med. May 2013;12(2):67-69.

• Sampath S, Mittal BR, Arun S, Sood A, Bhattacharya A, Sharma A. Usefulness of asymmetry score on quantitative three-phase bone scintigraphy in the evaluation of complex regional pain syndrome. Indian J Nucl Med. Jan 2013;28(1):11-16

• Santhosh S, Bhattacharya A, Harisankar CN, Kochhar R, Mittal BR. Role of 18F-FDG PET/CT in the Management of a Case of Autoimmune Pancreatitis With Extrapancreatic Manifestations. Clin Nucl Med. Mar 18 2013.

• Santhosh S, Kashyap R, Bhattacharya A, Kumar Jindal S, Rai Mittal B. Role of F18 fluorodeoxyglucose positron-emission tomography/computed tomography in the management of Askin’s tumor. Indian J Nucl Med. Jul 2013;28(3):180-182.

• Santhosh S, Mittal BR, Bhasin D, et al. Role of (18)F-fluorodeoxyglucose positron emission tomography/computed tomography in the characterization of pancreatic masses: experience from tropics. J Gastroenterol Hepatol. Feb 2013;28(2):255-261.

• Santhosh S, Mittal BR, Raveendran A, et al. Plasmacytoma of the Ovary: Additional Role of 18F-FDG PET/CT. Clin Nucl Med. May 2013;38(5):e230-232.

• Jung RS, Mittal BR, Santhosh S, Sood A, Bhattacharya A, Kapoor R. Is femoral uptake of Tc99m-methylene diphosphonate on bone scintigraphy in bronchogenic carcinoma an alarming sign: A case report and brief review of literature? Lung India. Jul 2014;31(3):280-281.

• Raja S, Mittal BR, Santhosh S, Bhattacharya A, Rohit MK. Comparison of LVEF assessed by 2D echocardiography, gated blood pool SPECT, 99mTc tetrofosmin gated SPECT, and 18F-FDG gated PET with ERNV in patients with CAD and severe LV dysfunction. Nucl Med Commun. Nov 2014;35(11):1156-1161.

• Reddy AK, Santhosh S, Mittal BR, Bhattacharya A, Sharma SC. Isolated cerebellar hypermetabolism on FDG PET in a case of remitted primary breast lymphoma. Indian J Nucl Med. Jan 2014;29(1):55-56.

• Kamaleshwaran KK, Mittal BR, Santhosh S, Kashyap R, Bhattacharya A, Mete UK. Detection and response evaluation of penile metastasis from urinary bladder carcinoma demonstrated by F-18 FDG PET/CT. Indian J Cancer. 2014 July- September;51(3):391-392.

• Sahu KK, Uthamalingam P, Sampath S, et al. Ocular adnexal lymphomas: report of 2 cases of mantle cell lymphomas and short review of literature. Indian J Hematol Blood Transfus. Sep 2014;30(3):163-168.

• Santhosh S, Mittal BR, Bhasin D, et al. Dual-phase 18F-FDG PET/CT imaging in the characterization of pancreatic lesions: does it offer prognostic information? Nucl Med Commun. Oct 2014;35(10):1018-1025.

• Santhosh S, Mittal BR, Gayana S, Bhattacharya A, Sharma A, Jain S. F-18 FDG PET/CT in the evaluation of Takayasu arteritis: An experience from the tropics. J Nucl Cardiol. Oct 2014;21(5):993-1000.

• Santhosh S, Mittal BR, Rana SS, et al. Metabolic signatures of malignant and non-malignant mass-forming lesions in the periampulla and pancreas in FDG PET/CT scan: an atlas with pathologic correlation. Abdom Imaging. 2015 Jun;40(5):1285-315. PubMed PMID: 25296997.

• Lad D, Malhotra P, Maskey D, Santhosh S, et al. Pyrexia, Lung nodules, Granulomas: Pulmonary Lymphomatoid Granulomatosis. Indian J Hematol Blood Transfus. Sep 2014;30(Suppl 1):418-421.

• Santhosh S, Bhattacharya A, Rana SS, Bhasin DK, Srinivasan R, Mittal BR. Pancreatic tuberculosis: Evaluation of therapeutic response using F-18 fluoro-2- deoxy-D-glucose positron emission tomography/computed tomography. Indian J Nucl Med. Oct 2014;29(4):257-259.

• Rana SS, Sharma V, Sampath S, Sharma R, Mittal BR, Bhasin DK. Vascular invasion does not discriminate between pancreatic tuberculosis and pancreatic malignancy: a case series. Annals of Gastroenterology. 2014;27(4):395-398.

• Santhosh S, Mittal BR, Kang M, Kapoor R, Gupta R, Rana S, Bhattacharya A, Bhasin D: Diagnostic accuracy of F-18 FDG PET/CECT vs. CECT for detecting recurrence of periampullary carcinoma and its prognostic significance. Abdom Imaging. 2015 Jun;40(5):1131-7. PubMed PMID: 25655637.

• Rana SS, Chaudhary V, Sharma V, Sharma R, Gupta N, Sampath S, Mittal BR, Gupta R, Dutta U, Bhasin DK. Unusual cause of obstructive jaundice revealed by endoscopic ultrasound guided fine-needle aspiration of mediastinal lymph node. Endosc Ultrasound. 2015 Jan-Mar;4(1):73-5. PubMed PMID: 25789290; PubMed Central PMCID: PMC4362010.

• Santhosh S, Bahl A, Saikia UN, Lad D, Mittal BR, Malhotra P, Varma S. FDG PET/CT in the staging and follow-up of primary cardiac ‘T’ cell lymphoma presenting as hypertrophic cardiomyopathy. J Nucl Cardiol. 2016 Jun;23(3):581-4. PubMed PMID: 26160589.

• Santhosh S, Lakshmanan RK, Sonik B, Padmavathy R, Gunaseelan RE. Contrast-enhanced fluorodeoxyglucose positron emission tomography/computed tomography in solid pseudopapillary neoplasm of the pancreas. Indian J Nucl Med. 2016 Apr-Jun;31(2):131-3. PubMed PMID: 27095862; PubMed Central PMCID: PMC4815386.

• Santhosh S, Bhattacharya A, Verma RK, Lal A, Mittal BR. A rare case of asymptomatic radioiodine-avid renal and brain metastases 20 years after hemithyroidectomy for adenomatous goiter. Indian J Nucl Med. 2016 Jan-Mar;31(1):42-4. PubMed PMID: 26917894; PubMed Central PMCID: PMC4746841.

• Santhosh S, Bhattacharya A, Rana SS, Bhasin DK, Gupta R, Mittal BR. Noninvasive evaluation of active pan-ulcerative colitis with multiple strictures using Fluorine-18-Fluorodeoxyglucose positron emission tomography/computed tomography. Indian J Nucl Med. 2016 Jan-Mar;31(1):65-6. PubMed PMID: 26917901; PubMed Central PMCID: PMC4746848.

• Santhosh S, Gorla AK, Bhattacharya A, Varma SC, Mittal BR. Contrastenhanced fluorodeoxyglucose positron emission tomography/contrast-enhanced computed tomography in mediastinal T-cell lymphoma with superior vena cava syndrome. Indian J Nucl Med. 2016 Jan-Mar;31(1):79-80. PubMed PMID: 26917907; PubMed Central PMCID: PMC4746854.

• Santhosh S, Mittal BR, Bhasin DK, Rana SS, Gupta R, Das A, Nada R. Fluorodeoxyglucose-positron emission tomography/computed tomography performs better than contrast-enhanced computed tomography for metastasis evaluation in the initial staging of pancreatic adenocarcinoma. Ann Nucl Med. 2017
• Agrawal K, Tripathy SK, Sen RK, Santhosh S, Bhattacharya A. Nuclear medicine imaging in osteonecrosis of hip: Old and current concepts World J Orthop 8(10):747-753.

Experience

• Consultant – Nuclear Medicine
  Dr. Rela Institute & Medical Centre (RIMC), Chennai
  Present

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