Pancreas transplantation for treatment of diabetes has evolved significantly since its inception in 1960’s. Most pancreas transplant recipients find the transition for transplantation easier than continued insulin therapy. There is enough compelling evidence that pancreas transplant is not only acutely life-enhancing, but also life-saving. Although other complementary therapies are currently actively being investigated for the treatment of diabetes such as implantable insulin pumps, gene therapy and artificial pancreas, there is currently none proven to be more beneficial than a pancreas transplant. It goes without saying that pancreas transplant offers the ‘best medical therapy’ for type 1 diabetes and selected type 2 diabetes patients.

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