Dr. Julius Xavier Scott

Educational Qualifications

• Fellowship in Paediatric Hemato-Oncology
  Women’s and Children’s Hospital, Adelaide, Australia
  2009
• DNB (Paediatrics)
  National Board of Examinations, India
  2001
• MD (Paediatrics)
  Tamil Nadu Dr. M.G.R. Medical University
  2000
• DCH
  Tamil Nadu Dr. M.G.R. Medical University
  1997
• MBBS
  Tamil Nadu Dr. M.G.R. Medical University
  1993

Clinical Expertise

PRIMARY IMMUNODEFICIENCIES

Bone Marrow & Stem Cell Procedures

• Allogenic Paediatric Bone Marrow Transplantation
• Autologous Paediatric Bone Marrow Transplantation
• Bone Marrow Harvesting
• Bone Marrow Aspiration & Biopsy
• Stem Cell Collection & Processing
• Cord Blood Transplantation
• Leukapheresis

Cancer Diagnosis & Targeted Therapy

• Lumbar Puncture (with/without Intrathecal Chemotherapy)
• High-dose Chemotherapy Administration
• PICC Line
• Central Venous Catheter

Post-Transplant & Supportive Care

• Graft-versus-Host Disease (GVHD) Management
• Paediatric Intensive Care Support During Transplant
• Infection Prevention in Immunocompromised Children

Childhood Blood Disorders

• Aplastic Anaemia including Inherited Bone Marrow Failure Syndromes
  • Fanconi Anaemia
  • Diamond–Blackfan Anaemia

• Anemias including nutritional, hemolytic and pure red cells aplasia
• Thalassaemia Major
• Sickle Cell Anaemia
• Immune thrombocytopenia (ITP)
• Bleeding disorders including Hemophilia and other rare coagulation disorders
• Paediatric thrombosis
• Eosinophilia/Neutropenia related disorders

Childhood Cancers & Leukaemias

• Childhood Leukaemias
  • ALL: Acute Lymphoid Leukaemia
  • AML: Acute Myeloid Leukaemia
  • CML (Chronic Myeloid Leukemia) and JMML (Juvenile Myelomonocytic Leukemia)
• Lymphomas (Hodgkin’s, Non-Hodgkin’s)
• Solid tumours including neuroblastoma, germ cell tumour, Wilms tumour, sarcoma, bone tumour and brain tumours, Retinoblastoma
• Relapsed/Refractory Childhood Cancers

Rare & Genetic Disorders

• Primary Immunodeficiency Disorders
  • SCID: Severe Combined Immunodeficiency.
  • Wiskott–Aldrich Syndrome
  • HLH: Hemophagocytic Lymphohistiocytosis
  • ALPS: Autoimmune Lymphoproliferative Syndrome
  • XLA: X-linked Agammaglobulinemia
  • CGD: Chronic Granulomatous Disease
  • LAD: Leukocyte Adhesion Deficiency
  • Hyper IgM or Hyper IgE syndrome
  • ALPS: Autoimmune Lymphoproliferative Syndrome
  • MSMD: Mendelian Susceptibility to Mycobacterial Disease
  • Interleukin defects
• Metabolic & Storage Disorders
  • Hurler’s Syndrome
  • Adrenoleukodystrophy
  • Krabbe Disease
  • Gaucher’s Disease
• Myelodysplastic Syndromes

Accomplishments

Affiliations and Memberships

Present position

Honors and Awards

Editorial Work and Reviewer

Innovation

Associated Publications

Research and Publication

Peer-Reviewed Journal Articles

• Osteonecrosis in an adolescent with leukemia treated with steroids. Sri Lankan Journal of Child Health. JX Scott, Latha MS, Sabitha C, Sugaprya V, Prabhu R.
  
• Sneha LM, Sai J, Ashwini S, Ramaswamy S, Rajan M, Scott JX. Financial burden faced by families due to out-of-pocket expenses during the treatment of their cancer children: An Indian perspective. Indian J Med Paediatr Oncol. 38(1):4-9. doi:10.4103/0971-5851.203493. PMID: 28469329; PMCID: PMC5398105.
  
• Rajasekaran J, Tripathy J, Vij M, Scott JX. Unusual cause for testicular swelling in a child. BMJ Case Rep. doi:10.1136/bcr-2016-217656. PMID: 28446480.
  
• Venkatasai JP, Srinivasamaharaj S, Sneha LM, Scott JX, Baby AK, Rajan M. Pediatric hematological malignancy: Identification of issues involved in the road to diagnosis. South Asian J Cancer. 6(1):28-30. doi:10.4103/2278-330X.202559. PMID: 28413793; PMCID: PMC5379890.
  
• Shanmugam N, Scott JX, Kumar V, Vij M, Ramachandran P, Narasimhan G, Reddy MS, Kota V, Munirathnam D, Kelgeri C, Sundaram K, Rela M. Multidisciplinary management of hepatoblastoma in children: Experience from a developing country. Pediatr Blood Cancer. 64(3). doi:10.1002/pbc.26249. PMID: 27781375.
  
• Mohan G, Scott JX, Nasrin R, Sneha L, Manohar R, Subramanian L, Narayani S, Rajendran A. First counseling revealing the diagnosis of childhood cancer: Parent preferences from an Indian perspective. J Pediatr Hematol Oncol. 38(8):622-626. PMID: 27769080.
  
• Latha SM, Scott JX, Kumar S, Kumar SM, Subramanian L, Rajendran A. Parent’s perspectives on the end-of-life care of their child with cancer: Indian perspective. Indian J Palliat Care. 22(3):317-325. doi:10.4103/0973-1075.185047. PMID: 27559262; PMCID: PMC4973494.
  
• Ravikumar R, Manohar R, Latha SM, Scott JX. Gingival hypertrophy in a child: Expect the unexpected. Indian J Dent. 7(2):112-4. doi:10.4103/0975-962X.180317. PMID: 27433057; PMCID: PMC4934087.
  
• Jayabose S, Viswanathan K, Kumar V, Annamalai A, Srinivasan A, Scott JX, Rathnam K. ABVE-PC and modified BEACOPP regimen in Indian children with Hodgkin lymphoma: Feasibility and efficacy. Indian J Med Paediatr Oncol. 37(2):106-11. doi:10.4103/0971-5851.180142. PMID: 27168709; PMCID: PMC4854041.
  
• Srinivasan A, Satish G, Scott JX, Madhavan R, Sathiyasekaran M. Two uncommon paraneoplastic neurological syndromes in a child with Hodgkin lymphoma. J Pediatr Hematol Oncol. 38(6). doi:10.1097/MPH.00000000000569. PMID: 27164530.
  
• Mohan R, Mohan G, Scott JX, Rajendran A, Paramasivam V, Ravindran M. Vitamin D insufficiency among children with cancer in India.
• Gayatri SA, Lily Daniela, Vaishnavi RA, Scott JX, Aruna Rajendran. Subgaleal bleed and bilateral proptosis as an initial manifestation of mild hemophilia A in a child. Sri Ramachandra Journal of Medicine / IOSR Journal of Dental and Medical Sciences.
• Archana P Kumar, Julius Xavier Scott J, Rajendiran A, Vijayaraghavan PV. Need assessment for curriculum on professionalism among undergraduate medical students. Int. J. Pure Appl. Biosci. 3(2):279-285.
  
• Rajendran P, Karmegaraj B, Vij M, Scott JX. Unusual cause for gum hypertrophy and skin nodules in a child. BMJ Case Rep. doi:10.1136/bcr-2015-211506. PMID: 26682835.
  
• Rajendran R, Suman FR, Rajendran A, Scott JX. Co-incidence or co-existence? Acute lymphoblastic leukaemia in HbE-alpha thalassaemia: A case report with review of literature. J Clin Diagn Res. 9(11):XD01-XD02. doi:10.7860/JCDR/2015/14711.6796. PMID: 26672845; PMCID: PMC4668511.
  
• Sneha LM, Nagarajan VP, Karmegaraj B, Rao S, Manipriya R, Scott JX. Kimura’s Disease: A rare cause of chronic lymphadenopathy in a child. Malays J Med Sci. 22(2):69-72. PMID: 26023299; PMCID: PMC4438096.
  
• Latha MS, Chitralakshmi K, Ravindran M, Angeline PR, Kannan L, Scott JX. Knowledge, attitude, and awareness of childhood cancer among undergraduate medical students in South India. South Asian J Cancer. 4(2):75-7. doi:10.4103/2278-330X.155680. PMID: 25992346; PMCID: PMC4418087.
  
• Raja S, Suman FR, Scott JX, Latha MS, Rajenderan A, Ethican A. Pancytopenia – An obstacle in the diagnosis and outcome of pediatric acute lymphoblastic leukemia. South Asian J Cancer. 4(2):68-71. doi:10.4103/2278-330X.155648. PMID: 25992344; PMCID: PMC4418085.
  
• Sneha LM, Karmegaraj B, Ravindran M, Srikiran S, Sai V, Scott JX. All that seems to be miliary mottling is not always due to tuberculosis: A case report. Trop Doct. PMID: 25914410.
  
• Latha SM, Krishnaprasadh D, Murugapriya P, Scott JX. Single dose rasburicase in the management of tumor lysis syndrome in childhood acute lymphoblastic leukemia: A case series. Indian J Nephrol. 25(2):91-4. doi:10.4103/0971-4065.139092. PMID: 25838646; PMCID: PMC4379632.
  
• Srinivasan A, Tiwari K, Scott JX, Ramachandran P, Ramakrishnan M. Impact of cancer support groups on childhood cancer treatment and abandonment in a private pediatric oncology centre. Indian J Palliat Care. 21(1):68-71. doi:10.4103/0973-1075.150192. PMID: 25709189; PMCID: PMC4332131.
  
• Punnen A, Loganathan SK, Veetiyil GI, Scott JX, Kumar S. Neonate with orbital bleed. Pediatr Blood Cancer. 62(3):548. doi:10.1002/pbc.25339. PMID: 25447027.
  
• Suresh N, Uppuluri R, Geetha J, Vasanthi T, Scott JX. Hemophagocytic lymphohistiocytosis masking the diagnosis of lymphoma in an adolescent male. Indian J Hematol Blood Transfus. 30(Suppl 1):135-7. doi:10.1007/s12288-013-0291-y. PMID: 25332560; PMCID: PMC4192262.
  
• Latha MS, Rajendran A, Pasupathy U, Scott JX. Acute transient parotitis in a child with primitive neuroectodermal tumor after a standard dose etoposide. Indian J Med Paediatr Oncol. 35(1):124. doi:10.4103/0971-5851.133744. PMID: 25006307; PMCID: PMC4080655.
  
• Thirugnanasambandam RP, Latha MS, Moorthy A, Kannan L, Paramasivam V, Scott JX. Attitude of postgraduates in general pediatrics toward pediatric oncology subspecialty as a career. Indian J Med Paediatr Oncol. 35(1):71-4. doi:10.4103/0971-5851.133725. PMID: 25006288; PMCID: PMC4080667.
  
• Karmegaraj B, Latha MS, Manipriya R, Vijayakumar S, Rajendran A, Maljetty V, Samikannu R, Scott JX. Periorbital chloroma mimicking raccoon eyes in a child with acute myeloid leukaemia. Arch Dis Child. 99(11):1025. doi:10.1136/archdischild-2014-306149. PMID: 24861047.
  
• Latha MS, Thirugnanasambandam RP, Balakrishnan N, Meghanathan HS, Moorthy A, Venkatraman P, Paramasivam V, Scott JX. Need of pediatric palliative care education among pediatric postgraduates in South India. Indian J Pediatr. 81(5):455-9. doi:10.1007/s12098-013-1295-1. PMID: 24408397.

Books Authored / Edited

• SCOTT’s PEDIA-TRICKS – Textbook of Pediatrics (Chief Editor; ~5,000 copies sold).
  
• Paediatric Oncology Manual for House Officer (2015).
  

Book Chapters

• Chronic Myelogenous Leukemia – Malignancies in Children, Postgraduate Textbook of Pediatrics.
  
• Renal Tumours in Neonates – Fetal & Neonatal Hematology and Oncology.
• Lung Tumors.
  
• Rhabdomyosarcoma Update – Textbook of Solid Tumors.
• Nutrition in Pediatric Oncology – Manual of Nutrition.

Experience

• Director, Department of Paediatric Hemato-Oncology
  Rela Hospital, Chennai
  
• Head, Department of Paediatric Hematology and Oncology
  Sri Ramachandra Medical University, Chennai
• Visiting Consultant – Paediatric Hemato-Oncology
  Kanchi Kamakoti Childs Trust Hospital, Chennai
• Visiting Consultant – Retinoblastoma Care (Paediatric Oncology Support)
  Sankara Nethralaya Eye Hospital, Chennai

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